Rated 4.6 out of 5 stars
200 Reviews
Supports the healthy breakdown of food-derived histamine


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  • Offers the patented enzyme formula containing diamine oxidase (DAO)
  • Is clinically proven to break down food-derived histamine in the digestive tract
  • Supports a healthy immune and inflammatory response to ingested histamine
  • Is easy to use, just take 1-2 capsule before a meal containing high histamine food
Rated 4.6 out of 5 stars
Based on 200 reviews
Total 5 star reviews: 159 Total 4 star reviews: 23 Total 3 star reviews: 9 Total 2 star reviews: 2 Total 1 star reviews: 7
89%would recommend this product
200 reviews
  • RC
    Rita C.
    Verified Buyer
    1 week ago
    Rated 5 out of 5 stars
    It’s A Journey

    Tiny, yet it works! Symptoms have improved greatly.

  • SA
    Sherril A.
    Verified Buyer
    1 week ago
    Rated 5 out of 5 stars

    Delivers as promoted!

  • EM
    Ellen M J.
    Verified Buyer
    1 month ago
    Rated 4 out of 5 stars
    My Results

    I'm pleased that the Histazyme has helped me. I have a lot of problems with diarrhea. I'm having fewer bouts with this issue. I'm having difficulty figuring out the best approach with this supplement. I need to figure out the frequency for me and I also need to study your reports about leaky gut. I'm reordering your product. Thanks

  • A
    2 months ago
    Rated 5 out of 5 stars
    5 Stars

    Excellent DAO product for high histamines. Especially with each tab having 20,000 IU dao is excellent standard of anti histamine supplement.

  • MM
    MARY M.
    Verified Buyer
    2 months ago
    Rated 5 out of 5 stars
    Amazing results!

    I love drinking wine with dinner and at parties, but suffer afterwards with headache, inflammation and joint pain. Taking this tiny pill before embibing, keeps all those after-effects at bay! It is pricey for sure, so try to get it on sale or redeem points for a discount.

    AM Profile picture for Amy Myers MD
    Amy Myers MD
    2 months ago

    Thank you Mary for your review of our Histazyme as we are so glad to hear that this supplement has shown some positive effects for your personal use!

    We hope that this supplement continues to support you with food-derived histamine and thanks again for your individual success story!

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