“I have noticed a visible reduction in fine lines near my eyes and mouth!”

Age-Defying Hyaluronic Acid Serum

Rated 4.8 out of 5 stars
23 Reviews
Reduces fine lines for youthful beauty



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rippled water

Hydrates Skin

Your skin loses its natural ability to retain essential moisture as you age. Hyaluronic acid, jojoba esters, and glycolic acid quickly penetrate your skin’s hydrolipidic barrier to deliver a surge of long-lasting hydration to parched skin cells.


Rejuvenates Tired Skin

The Age-Defying Hyaluronic Acid Serum features exotic botanical extracts including white willow bark, horsetail grass, and wild geranium flower to promote the formation of healthy new skin cells to reduce the appearance of fine lines and wrinkles.

white layers

Supports Skin Elasticity

As we age, our natural production of collagen decreases, resulting in tired-looking, saggy skin. Hyaluronic acid binds to existing collagen, restoring essential moisture to promote a noticeably plump, dewy, and hydrated complexion.

pink hexagons

Promotes Skin Cell Turnover

The Age-Defying Hyaluronic Acid Serum contains purifying glycolic acid, which dissolves epithelial cells on your skin’s surface to reveal fresh cells untouched by sun damage or affected by discoloration, so you present a bright, clear complexion.

woman smiling

Purifies Clogged Pores

The Age-Defying Hyaluronic Acid Serum contains anti-aging and skin-clearing vitamin A to increase skin cell turnover and clear dead skin cells to shrink pore size and reduce the appearance of fine lines and discoloration.


Soothes Irritated Skin

Organic green tea extract calms redness and swelling by eliminating dead skin cells and cleansing stubborn dirt, oil, and bacteria from clogged pores for soothed and nourished skin.

Key Ingredients

Hyaluronic Acid

Hyaluronic Acid binds to collagen, keeping essential moisture below your skin’s surface for dewy, taught, and youthful skin that radiates health.


Retinol refines pores and reduces the appearance of fine lines and discoloration while delivering unparalleled exfoliation.

Glycolic Acid

Glycolic Acid reveals brighter, clearer skin by dissolving excess epithelial cells at the surface and purifying congested pores.

FULL INGREDIENTS LIST: Aqua (Deionized Water), Hamamelis Virginiana Water (Witch Hazel), Organic Aloe Barbadensis Leaf Juice (Aloe Vera) Cassia Angustifolia Seed Polysaccharide (Plant Based Hyaluronic Acid), Glycerin (Kosher, Vegetable Glycerin), Santalum Austrocaledonicum Wood Water (Sandalwood Hydrosol), Retinol, Glycolic Acid, Hydroxyethyl Ethylcellulose, Jojoba Esters, Carrageenan, Thioctic Acid, Pentylene Glycol, Polysorbate 20, Simmondsia Chinensis (Organic Jojoba) Oil, Salix Alba Bark Extract (Willow Bark), Propolis Extract, Tocopheryl Acetate (Vitamin E), Organic Centella Asiatica Extract (Gotu Kola Extract), Lecithin, Potassium Sorbate, Sodium Benzoate, Phenoxyethanol, Ethylhexylglycerin, Camellia Sinensis (Organic Green Tea) Leaf Extract, Equisetum Arvense Extract (Horsetail Extract), Geranium Maculatum Extract (Wild Geranium), Taraxacum Officinale Extract (Dandelion Extract)

Our Clean Promise

We believe you shouldn’t have to compromise your standards when it comes to selecting  beauty products that work. The cosmetic industry argues that it’s perfectly fine to use toxic ingredients such as parabens, phthalates, and formaldehyde-releasing preservatives on your face because only tiny amounts are used in each product and are therefore not harmful. However, with daily use, these toxic chemicals add up and wreak havoc on your body and your health! Our high-performance, doctor-designed formulas are nontoxic and rich in the purest forms of bioactive botanical ingredients so you can experience healthy skin without sacrificing results!

How To Use

  1. Apply 1-4 pumps of the Age-Defying Hyaluronic Acid Serum onto freshly cleansed skin.
  2. Wait 30 seconds for it to absorb.
  3. Follow up with Hydrating Ceramide Cream for a surge of intense moisture.



When should I apply the Hyaluronic Acid Serum?

Apply the Age-Defying Hyaluronic Acid Serum during your morning and nighttime facial care routine after cleansing with the Replenishing VItamin C Cleanser. Follow up with the Hydrating Ceramide Cream.


Is this serum suitable for sensitive skin?

Amy Myers MD® Beauty rigorously patch tests all of our facial care products on a variety of skin types to ensure even those with the most sensitive skin will benefit. However, we recommend testing the product on the inside of your arm to see if your skin is prone to irritation with hyaluronic acid or retinol.


I’ve heard retinol can cause irritation, will this product?

If you’ve used retinol successfully in the past, you shouldn’t see any issues with the Age-Defying Hyaluronic Acid serum. First-time retinol users may experience irritation, including redness, dryness, and peeling. If you use too high a strength or apply retinol more frequently than you should, you may experience further irritation, like itchiness and scaly patches. We recommend testing the product on the inside of your arm to see if your skin is prone to irritation with retinol.

† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Rated 4.8 out of 5 stars
Based on 23 reviews
Total 5 star reviews: 22 Total 4 star reviews: 0 Total 3 star reviews: 0 Total 2 star reviews: 0 Total 1 star reviews: 1
96%would recommend this product
23 reviews
  • S
    27 minutes ago
    Rated 5 out of 5 stars
    5 Stars

    Great product

  • MR
    Margaret R.
    Verified Buyer
    4 months ago
    Rated 5 out of 5 stars
    Very pleased with this product

    This is my third time purchasing this product. I'm very pleased with the quality, just wish it wasn't so expensive. Learning about the benefits of hyaluronic acid, I recently began taking Pure Encapsulation hyaluronic acid supplement which has helped so, so much.

    Thankful that Dr. Myers makes the serum!

  • JR
    jo R.
    Verified Buyer
    6 months ago
    Rated 1 out of 5 stars
    Chapped the skin under my eyes

    It dried out my skin and created a worse eye bag situation ….my skin became rough and dry.

    AM Profile picture for Amy Myers MD
    Amy Myers MD
    6 months ago

    Hi Jo,

     We are so sorry to hear that the Hyaluronic Serum was not working out for you. 

    We will reach out to you with your email on file to offer further support and we look forward to connecting with you!

  • CB
    Candice B.
    Verified Buyer
    7 months ago
    Rated 5 out of 5 stars
    Great product!

    I could tell immediately that my face was less dry. By the morning, my skin felt renewed, moisturized, and clean. It’s not thick and heavy. A few drops after cleaning my face each night and after shower in the morning and I’m good to go. I get dry skin immediately when I stop using it.

  • MS
    Melanie S.
    Verified Buyer
    1 year ago
    Rated 5 out of 5 stars

    I like how it easily absorbs into my skin. This is the 3rd or 4th bottle that I have purchased.

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